Article
Polymorphisms in the CYP19 and AR genes--relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy: The Danish Osteoporosis Prevention Study.
Calcified tissue international - 1 Jan 2004
Tofteng C L, Kindmark A, Brändström H, Abrahamsen B, Petersen S, Stiger F, Stilgren L S, Jensen J E B, Vestergaard P, Langdahl B L, Mosekilde L
Abstract excerpt
Polymorphisms in the androgen receptor ( AR) gene and genes encoding enzymes involved in synthesis of sex steroids (e.g., the CYP19 gene encoding aromatase) have recently received attention in osteoporosis research. In the Danish Osteoporosis Prevention Study, recent postmenopausal women were allocated to either hormone replacement therapy (HRT) or no treatment. We genotyped 1792 women for the CYP19 (TTTA)(n)...
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