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Cyp17, urinary sex steroid levels and breast cancer risk in postmenopausal women.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2005

Onland-Moret N Charlotte, van Gils Carla H, Roest Mark, Grobbee Diederick E, Peeters Petra H M

Abstract excerpt

Endogenous sex hormones play an important role in the etiology of breast cancer. Polymorphisms in genes encoding for enzymes involved in steroidogenesis may therefore play a role in breast cancer risk. Cytochrome P450c17alpha (Cyp17) functions at key branch points in human steroidogenesis. A T-->C transition (A1 and A2 allele) in the 5' untranslated region may be associated with increased expression of Cyp17....

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PMID: 15824149
DOI: 10.1158/1055-9965.EPI-04-0197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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