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Article

CYP17 gene polymorphisms: prevalence and associations with hormone levels and related factors. a HuGE review.

American journal of epidemiology - 15 Oct 2004

Sharp L, Cardy A H, Cotton S C, Little J

Abstract excerpt

The cytochrome P-450c17alpha (CYP17 ) gene, located on chromosome 10q24.3, encodes the enzyme cytochrome P-450c17alpha, which functions at key branch points in steroid hormone biosynthesis. Three polymorphisms have been described, but only the single base-pair change in the 5'-untranslated region (5'-UTR) has been investigated to any great extent. In single studies, the variant was associated with reduced...

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Identifiers

PMID: 15466495
DOI: 10.1093/aje/kwh287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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