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Article

Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2004

Tworoger Shelley S, Chubak Jessica, Aiello Erin J, Ulrich Cornelia M, Atkinson Charlotte, Potter John D, Yasui Yutaka, Stapleton Patricia L, Lampe Johanna W, Farin Federico M, Stanczyk Frank Z, McTiernan Anne

Abstract excerpt

Women with high circulating estrogen concentrations have an increased risk of breast cancer; thus, it is important to understand factors, including genetic variability, that influence estrogen concentrations. Several genetic polymorphisms that may influence sex hormone concentrations have been id...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14744739
DOI: 10.1158/1055-9965.epi-03-0026

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14744739-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women.PMID 14744739Read ↗

Polymorphisms associated with circulating sex hormone levels in postmenopausal women.Semantic proximity Read ↗

Polymorphisms in CYP17, COMT, and ESR1 genes in women after menopause and association with bone mineral density.Semantic proximity Read ↗

Association of genetic polymorphisms with serum estrogens measured multiple times during a 2-year period in premenopausal women.Semantic proximity Read ↗

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Differences in 4-hydroxyestradiol levels in leukocytes are related to CYP1A1(∗)2C, CYP1B1(∗)3 and COMT Val158Met allelic variants.Semantic proximity Read ↗

CYP17 gene polymorphisms: prevalence and associations with hormone levels and related factors. a HuGE review.Semantic proximity Read ↗

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Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women.Semantic proximity Read ↗

Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility.Semantic proximity Read ↗

Two single nucleotide polymorphisms in the CYP17 and COMT Genes--relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy. The Danish Osteoporosis Prevention Study.Semantic proximity Read ↗

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