Article
Association of the (TTTA)n repeat polymorphism of CYP19 gene with bone mineral density in Greek peri- and postmenopausal women.
Clinical endocrinology - 1 Jul 2014
Markatseli Anastasia E, Lazaros Leandros, Markoula Sofia, Kostoulas Harilaos, Sakaloglou Prodromos, Tigas Stelios, Georgiou Ioannis, Tsatsoulis Agathocles
Abstract excerpt
UNLABELLED: Aromatase is encoded by the CYP19 gene and catalyses the conversion of androgens to oestrogens, which in turn regulate skeletal homeostasis. CYP19 gene polymorphisms have been studied for their association with bone mineral density (BMD) in the general population with mixed results. OBJECTIVE: To explore the influence of the CYP19 (TTTA)n repeat polymorphism on BMD and serum levels of osteoprotegerin...
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