Article
Polymorphisms in CYP17, COMT, and ESR1 genes in women after menopause and association with bone mineral density.
Genetics and molecular research : GMR - 2 Dec 2015
Gonçalves C G, Almeida B C, Camargo-Kosugi C M, Costa A M M, Silva I D C G, Haidar M A
Abstract excerpt
In this study, we evaluated genetic factors related to the mineral density during post-menopause. We evaluated 110 women in the first 5 years post-menopause, without previous hormone replacement therapy. Cytochrome P450 17 (CYP17) (rs743572), catechol-O-methyl transferase (COMT) (rs4680), and estrogen receptor 1 (ESR1) (rs9322331) were examined for the presence of polymorphisms. Clinical data were collected by...
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