Article
The COMT val158met polymorphism is associated with peak BMD in men.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2004
Lorentzon Mattias, Eriksson Anna-Lena, Mellström Dan, Ohlsson Claes
Abstract excerpt
UNLABELLED: The associations between the functional val158met polymorphism of the estrogen-degrading COMT enzyme and skeletal properties in young men were investigated. BMD was associated with COMT genotype. INTRODUCTION: Peak BMD is an important predictor of future risk of osteoporosis, and it is to a large extent determined by genetic factors. Estrogens are involved in the accretion of bone mass during puberty....
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