Article
Prepulse inhibition deficits in GAD65 knockout mice and the effect of antipsychotic treatment.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Sept 2004
Heldt Scott A, Green Amanda, Ressler Kerry J
Abstract excerpt
Recent postmortem studies in humans suggest that defects in GABAergic neurotransmission might contribute to the neuropathology associated with schizophrenia. Disturbances in GABAergic systems may also contribute to the sensorimotor gating deficits classically observed in schizophrenic patients, including deficits in prepulse inhibition (PPI). To explore the relationship, the current study examined the integrity...
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