Article
Prepulse startle deficit in the Brown Norway rat: a potential genetic model.
Behavioral neuroscience - 1 Apr 2000
Palmer A A, Dulawa S C, Mottiwala A A, Conti L H, Geyer M A, Printz M P
Abstract excerpt
Prepulse inhibition (PPI), an operational measure of sensorimotor gating, is deficient in schizophrenia patients. PPI was compared among 4 strains of rats: Sprague-Dawley, Spontaneously Hypertensive, Wistar Kyoto (WKY), and Brown Norway (BN). PPI was dramatically lower in BN versus the other strains, especially WKY, for both acoustic and airpuff startle stimuli, whereas startle amplitude was similar between BN...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
