Article
Behavioral abnormalities in synapsin II knockout mice implicate a causal factor in schizophrenia.
Synapse (New York, N.Y.) - 1 Aug 2009
Dyck Bailee A, Skoblenick Kevin J, Castellano Jessica M, Ki Kitty, Thomas Nancy, Mishra Ram K
Abstract excerpt
Recent studies on the phosphoprotein synapsin II have revealed reduced expression in postmortem medial prefrontal cortex tissues from subjects with schizophrenia, and chronic antipsychotic drug treatment has resulted in concurrent increases in synapsin II mRNA and protein levels. Collectively, th...
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