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Article

Mouse genetic models for prepulse inhibition: an early review.

Molecular psychiatry - 1 Jan 2002

Geyer M A, McIlwain K L, Paylor R

Abstract excerpt

Prepulse inhibition (PPI) is the phenomenon in which a weak prepulse stimulus attenuates the response to a subsequent startling stimulus. Patients with schizophrenia and some other neuropsychiatric disorders have impaired PPI. Impaired PPI in these patient populations is thought to reflect dysfunctional sensorimotor gating mechanisms. Recently, various inbred mouse strains and genetically modified mouse lines...

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Identifiers

PMID: 12476318
DOI: 10.1038/sj.mp.4001159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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