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Article

Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 May 2009

Karlsson Rose-Marie, Tanaka Kohichi, Saksida Lisa M, Bussey Timothy J, Heilig Markus, Holmes Andrew

Abstract excerpt

Glutamatergic dysfunction is increasingly implicated in the pathophysiology of schizophrenia. Current models postulate that dysfunction of glutamate and its receptors underlie many of the symptoms in this disease. However, the mechanisms involved are not well understood. Although elucidating the...

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Identifiers

PMID: 19078949
DOI: 10.1038/npp.2008.215
PMCID: PMC3400972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19078949-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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