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Article

Interactions of the mGluR5 gene with breeding and maternal factors on startle and prepulse inhibition in mice.

Neurotoxicity research - 1 Jan 2004

Brody Suzanne A, Geyer Mark A

Abstract excerpt

Sensorimotor gating, measured by prepulse inhibition (PPI), is a fundamental form of information processing that is deficient in schizophrenia patients and mice lacking the gene for metabotropic glutamate receptor 5 (mGluR5). Both breeding strategies and mothering behaviors are capable of influencing the behavioral phenotype of knockout (KO) mice. Previous studies found a PPI deficit and increased startle...

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Identifiers

PMID: 15184109
DOI: 10.1007/BF03033300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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