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Article

Sensorimotor gating of schizophrenia patients is influenced by 5-HT2A receptor polymorphisms.

Biological psychiatry - 1 Sept 2008

Quednow Boris B, Kühn Kai-Uwe, Mössner Rainald, Schwab Sibylle G, Schuhmacher Anna, Maier Wolfgang, Wagner Michael

Abstract excerpt

BACKGROUND: Schizophrenia patients exhibit impairment in prepulse inhibition (PPI) of the acoustic startle response (ASR), suggesting a sensorimotor gating deficit. The serotonin-2A receptor (5-HT(2A)R) has been implicated in both the pathogenesis of schizophrenia and the PPI deficits of schizoph...

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Share to Acoustic Stimulation
Share to Gait Disorders, Neurologic
Share to Habituation, Psychophysiologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Inhibition, Psychological

Share to Psychiatric Status Rating Scales

Share to Receptor, Serotonin, 5-HT2A

Share to Reflex, Startle

Source

Identifiers

PMID: 18420180
DOI: 10.1016/j.biopsych.2008.02.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18420180-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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