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Article

T cell receptors: affinities, cross-reactivities, and a conformer model.

Molecular immunology - 1 Feb 2004

Holler Phillip D, Kranz David M

Abstract excerpt

Based on findings with the T cell receptor from mouse CTL clone 2C, and other TCRs, we propose a model that could account for degeneracy of T cell recognition. This "conformer model" holds that a single TCR exists in multiple conformations that are in equilibrium. The model is consistent with (1) the characterization of multiple ligands that bind to the 2C TCR, and other TCRs, (2) the binding properties and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15036906
DOI: 10.1016/j.molimm.2003.11.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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