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Biology-based AI Predicts T-cell Receptor Antigen Binding Specificity

2024-03-26

Abstract excerpt

Adoptive cell transfer (ACT) using T cells modified by the T cell receptor (TCR) gene is an exciting and rapidly developing field. Numerous preclinical and clinical studies have shown varying feasibility, safety, and efficacy of using TCR-engineered T cells to treat cancer and viral infections. Although there is evidence that their use is effective, to what extent and how these therapies can be improved is still a...

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Literature Corpus work
7fd135d6-1b0e-5777-94dc-a4ee6c18ab97
DOI
10.54097/wy28c490
Open publication

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Biology-based AI Predicts T-cell Receptor Antigen Binding SpecificityDOI 10.54097/wy28c490
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