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Article

Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene.

Journal of virology - 1 Apr 2004

Khan Nasser, Guarnieri Michael, Ahn Sang Hoon, Li Jisu, Zhou Yonghong, Bang Genie, Kim Kyun-Hwan, Wands Jack R, Tong Shuping

Abstract excerpt

Alteration in hepatitis B virus (HBV) secretion efficiency may have pathological consequences. Naturally occurring mutations that regulate virion secretion have not been defined. We recently identified HBV genomes displaying high (4B), substantially reduced (3.4), or negative (4C) virion secretion. In the present study, the underlying mutations were mapped. A T552C point mutation in the 4B genome was responsible...

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Share to Amino Acid Sequence
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Viral

Share to Hepatitis B Surface Antigens

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Source

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Identifiers

PMID: 15016847
DOI: 10.1128/jvi.78.7.3262-3270.2004
PMCID: PMC371066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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