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Article

Virion Secretion of Hepatitis B Virus Naturally Occurring Core Antigen Variants.

Cells - 30 Dec 2020

Shih Chiaho, Wu Szu-Yao, Chou Shu-Fan, Yuan Ta-Tung Thomas

Abstract excerpt

In natural infection, hepatitis B virus (HBV) core protein (HBc) accumulates frequent mutations. The most frequent HBc variant in chronic hepatitis B patients is mutant 97L, changing from an isoleucine or phenylalanine to a leucine (L) at HBc amino acid 97. One dogma in the HBV research field is that wild type HBV secretes predominantly virions containing mature double-stranded DNA genomes. Immature genomes,...

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Identifiers

PMID: 33396864
DOI: 10.3390/cells10010043
PMCID: PMC7823318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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