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Article

Mechanism of HBV genome variability and replication of HBV mutants.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2005

Tong Shuping

Abstract excerpt

Naturally occurring mutations in the H13V genome have been extensively documented, yet the biological consequences of even the dominant mutations have not been well characterized. In a recent study of HBeAg-positive French patients infected with genotype A, we obtained full-length clones with high or low replication capacities in the transfected human hepatoma cells. Surprisingly, high replicating clones were all...

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Share to Hepatitis B Core Antigens
Share to Gene Expression Regulation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Viral

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Share to Hepatitis B virus

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Share to Promoter Regions, Genetic

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Identifiers

PMID: 16461214
DOI: 10.1016/s1386-6532(05)80023-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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