Infection process of the hepatitis B virus depends on the presence of a defined sequence in the pre-S1 domain.

doi:10.1128/JVI.73.3.2052-2057.1999

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Article

Infection process of the hepatitis B virus depends on the presence of a defined sequence in the pre-S1 domain.

Journal of virology - 1 Mar 1999

Le Seyec J, Chouteau P, Cannie I, Guguen-Guillouzo C, Gripon P

Abstract excerpt

During the life cycle of hepatitis B virus (HBV), the large envelope protein (L) plays a pivotal role. Indeed, this polypeptide is essential for viral assembly and probably for the infection process. By performing mutagenesis experiments, we have previously excluded a putative involvement of the...

Topics

Hepatitis B Surface Antigens
Hepatitis B virus
Humans
Liver
Mutation
Protein Precursors
Tumor Cells, Cultured
Virion

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