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Article

Fhit is a physiological target of the protein kinase Src

8 Mar 2004

Abstract excerpt

The FHIT gene is a tumor suppressor that is frequently inactivated by genomic alterations at chromosomal region 3p14.2. In the last few years, a considerable amount of data describing inactivation of FHIT in a variety of human malignancies and demonstrating the tumor suppressor potential of Fhit have been reported. Despite the demonstration that FHIT functions as a tumor suppressor, the pathway through which Fhit...

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PMID: 15007172
DOI: 10.1073/pnas.0400481101

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