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Article

Allelic deletion analysis of the FHIT gene predicts poor survival in non-small cell lung cancer.

Cancer research - 15 Jun 1998

Burke L, Khan M A, Freedman A N, Gemma A, Rusin M, Guinee D G, Bennett W P, Caporaso N E, Fleming M V, Travis W D, Colby T V, Trastek V, Pairolero P C, Tazelaar H D, Midthun D E, Liotta L A, Harris C C

Abstract excerpt

The fragile histidine triad (FHIT) gene at chromosome 3p14.2 is a candidate tumor suppressor gene linked to cancers of the lung, breast, colon, pancreas, and head and neck. Reports of frequent allelic deletion and abnormal transcripts in primary lung tumors plus recent evidence that it is targete...

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Identifiers

PMID: 9635574

Genes

FHIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9635574-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Allelic deletion analysis of the FHIT gene predicts poor survival in non-small cell lung cancer.PMID 9635574Read ↗

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Aberration of FHIT gene is associated with increased tumor proliferation and decreased apoptosis-clinical evidence in lung and head and neck carcinomas.Semantic proximity Read ↗

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Aberrant methylation of the FHIT gene in chronic smokers with early stage squamous cell carcinoma of the lungSemantic proximity Read ↗

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Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering.Semantic proximity Read ↗

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