Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SRC: A Century of Science Brought to the Clinic

1 Aug 2010

Abstract excerpt

The SRC family kinases are the largest family of nonreceptor tyrosine kinases and one of the best-studied targets for cancer therapy. SRC, arguably the oldest oncogene, has been implicated in pathways regulating proliferation, angiogenesis, invasion and metastasis, and bone metabolism. More recently, researchers have proposed that the transforming ability of SRC is linked to its ability to activate key signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Myeloid Leukemia Treatments
Share to HER2/EGFR in Cancer Research
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20689754
DOI: 10.1593/neo.10328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SRC: A Century of Science Brought to the ClinicPMID 20689754Read ↗

The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors.Semantic proximity Read ↗

Src Continues Aging: Current and Future Clinical DirectionsSemantic proximity Read ↗

Src Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned So FarSemantic proximity Read ↗

SRC: Regulation, Role in Human Carcinogenesis and Pharmacological InhibitorsSemantic proximity Read ↗

Src Family Kinases: Potential Targets for the Treatment of Human Cancer and LeukemiaSemantic proximity Read ↗

Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transitionSemantic proximity Read ↗

Critical Roles of SRC-3 in Development and Progression of Breast Cancer, Render it a Prospective Clinical TargetSemantic proximity Read ↗

Exploring the potential value of SRC genes in pan cancer based on bioinformatics methodsSemantic proximity Read ↗

The Src signaling pathway: a potential target in melanoma and other malignanciesSemantic proximity Read ↗

The multifaceted therapeutic value of targeting steroid receptor coactivator-1 in tumorigenesisSemantic proximity Read ↗

SRC promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy.Semantic proximity Read ↗

Src kinase and pancreatic cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.