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Article

K-ras point mutations in human colorectal carcinomas: relation to aneuploidy and metastasis.

International journal of cancer - 19 Aug 1992

Suchy B, Zietz C, Rabes H M

Abstract excerpt

Material from paraffin sections of 109 human colorectal carcinomas, mostly obtained at autopsy, was analyzed for the presence of K-ras point mutations at codon 12, position 2. Mutations at this position were found in 23 cases (21.1%). Aneuploid colorectal carcinomas showed a significantly higher prevalence of K-ras point mutations than diploid tumors, suggesting an involvement of ras mutations in the development...

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Identifiers

PMID: 1500224
DOI: 10.1002/ijc.2910520107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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