Article
A relationship between K-ras gene mutations and some clinical and histologic variables in patients with primary colorectal carcinoma.
Clinical chemistry and laboratory medicine - 1 Jul 1999
Beránek M, Bures J, Palicka V, Jandík P, Langr F, Nejedlá E
Abstract excerpt
Mutations in the Kirsten ras 2 (K-ras) gene were described as early events in the process of colorectal carcinogenesis. The aim of this study was to find a possible relationship between the presence of K-ras mutation in samples of primary colorectal carcinomas and the clinico-pathological data of the investigated patients. Mutation in codon 12 of the K-ras gene was determined in 18 of 53 colorectal carcinomas...
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