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Article

Association of K-ras mutations with liver metastases from colorectal carcinoma.

Anticancer research - 1 Jan 2000

Tsunoda Akira, Iijima Takeru, Tsunoda Yuko, Nakao Kentaroh, Miyaki Michiko, Kusano Mitsuo

Abstract excerpt

BACKGROUND: Colorectal carcinomas were studied regarding early proof of liver metastases through determination of K-ras mutations. PATIENTS AND METHODS: Seventy-seven colorectal carcinomas were investigated for the presence of point mutations in codon 12 and 13 of the K-ras gene, using single-strand conformation polymorphism (SSCP) analysis and direct sequencing. RESULTS: Twenty-six carcinomas were positive for...

Topics

Adult
Aged
Aged, 80 and over
Colorectal Neoplasms
Female
Genes, ras
Genetic Predisposition to Disease
Humans
Liver Neoplasms
Male
Middle Aged
Point Mutation

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Predictive Value of Tests

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Identifiers

PMID: 15330200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15330200-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Association of K-ras mutations with liver metastases from colorectal carcinoma.PMID 15330200Read ↗

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