[Prevalence of K-ras gene mutations in human colorectal cancers].

Article

[Prevalence of K-ras gene mutations in human colorectal cancers].

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology - 1 Aug 1991

Hayakumo T, Azuma T, Nakajima M, Yasuda K, Cho E, Mukai H, Mizuma Y, Ashihara T, Mizuno S, Hirano S

Abstract excerpt

It has been reported that mutations in the human ras gene family convert these genes into active oncogenes. In the present study using in vitro gene amplification by the polymerase chain reaction (PCR) and mutation detection by the oligonucleotide hybridization assay, a total of 86 colorectal can...

Topics

Base Sequence
Codon
Colorectal Neoplasms
Female
Genes, ras
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation

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