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Article

[Prevalence of K-ras gene mutations in human colorectal cancers].

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology - 1 Aug 1991

Hayakumo T, Azuma T, Nakajima M, Yasuda K, Cho E, Mukai H, Mizuma Y, Ashihara T, Mizuno S, Hirano S

Abstract excerpt

It has been reported that mutations in the human ras gene family convert these genes into active oncogenes. In the present study using in vitro gene amplification by the polymerase chain reaction (PCR) and mutation detection by the oligonucleotide hybridization assay, a total of 86 colorectal cancers were analyzed for the point mutations at codon 12 and 13 of K-ras genes. Mutations were present in 33 of the 86...

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PMID: 1942608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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