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Article

A detailed analysis of K-ras point mutations in relation to tumor progression and survival in colorectal cancer patients

21 Jun 1996

Abstract excerpt

Point mutations in codon 12, 13, and 61 of the K-ras gene are an early event in tumorigenesis of colorectal cancer, but the impact of number, type, and position of such mutations on the progression of adenomas as well as the clinical behaviour of colorectal carcinomas is not clearly established. A series of 35 adenomas and 117 carcinomas at various stages was subjected to single-strand conformation polymorphism...

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Identifiers

PMID: 8682594
DOI: 10.1002/(sici)1097-0215(19960621)69:3<241::aid-ijc15>3.0.co;2-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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