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Article

p53 gene mutations in human endometrial carcinoma.

Molecular carcinogenesis - 1 Jan 1992

Risinger J I, Dent G A, Ignar-Trowbridge D, McLachlan J A, Tsao M S, Senterman M, Boyd J

Abstract excerpt

Although carcinoma of the uterine endometrium is the most frequently diagnosed malignancy of the female reproductive tract, the molecular genetic features of this tumor have yet to be described in significant detail. Since mutations of the p53 tumor suppressor gene are the single most common gene...

Topics

Alleles
Base Sequence
Chromosome Deletion
Codon
DNA, Neoplasm
Endometrial Neoplasms
Exons
Female
Genes, p53
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reference Values

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Identifiers

PMID: 1497800
DOI: 10.1002/mc.2940050403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1497800-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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p53 gene mutations in human endometrial carcinoma.PMID 1497800Read ↗

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Direct sequencing of the p53 gene shows absence of mutations in endometrioid endometrial adenocarcinomas expressing p53 protein.Semantic proximity Read ↗

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