Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 gene mutations in human endometrial carcinoma.

Molecular carcinogenesis - 1 Jan 1992

Risinger J I, Dent G A, Ignar-Trowbridge D, McLachlan J A, Tsao M S, Senterman M, Boyd J

Abstract excerpt

Although carcinoma of the uterine endometrium is the most frequently diagnosed malignancy of the female reproductive tract, the molecular genetic features of this tumor have yet to be described in significant detail. Since mutations of the p53 tumor suppressor gene are the single most common genetic alteration found in human malignancies, we examined the hypothesis that p53 mutations occur in human endometrial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 1497800
DOI: 10.1002/mc.2940050403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 gene mutations in human endometrial carcinoma.PMID 1497800Read ↗

The p53 tumor suppressor gene frequently is altered in gynecologic cancers.Semantic proximity Read ↗

Involvement of p53 gene mutations in human endometrial carcinomas.Semantic proximity Read ↗

Analysis of the p53 gene in human uterine carcinoma cell lines.Semantic proximity Read ↗

p53 mutation is a common genetic event in ovarian carcinoma.Semantic proximity Read ↗

Detection of p53 gene mutations in human ovarian and endometrial cancers by polymerase chain reaction-single strand conformation polymorphism analysis.Semantic proximity Read ↗

[Analysis of p53 gene in gynecologic tumors].Semantic proximity Read ↗

Mutation and allelic loss of the p53 gene in endometrial carcinoma. Incidence and outcome in 92 surgical patients.Semantic proximity Read ↗

Prevalence of allelic loss at TP53 in endometrial carcinomas.Semantic proximity Read ↗

Mutation of the p53 tumor-suppressor gene is not a feature of endometrial hyperplasias.Semantic proximity Read ↗

Direct sequencing of the p53 gene shows absence of mutations in endometrioid endometrial adenocarcinomas expressing p53 protein.Semantic proximity Read ↗

A novel loss-of-function mutation in TP53 in an endometrial cancer cell line and uterine papillary serous carcinoma model.Semantic proximity Read ↗

p53 Mutations in human hepatocellular carcinomas from Germany.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.