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Article

p53 mutations in esophageal tumors from high-incidence areas of China.

International journal of cancer - 29 May 1995

Liang Y Y, Estève A, Martel-Planche G, Takahashi S, Lu S H, Montesano R, Hollstein M

Abstract excerpt

Carcinomas of the upper digestive tract (squamous-cell carcinoma of the esophagus, adenocarcinoma of the cardia) from 24 patients residing in Linxian (China) and near-by high-incidence areas were analyzed for mutations in exons 5-8 of the p53 tumor-suppressor gene. Mutations were identified by polymerase chain reaction amplification and direct sequencing in 50% of the specimens. Eleven tumors harbored a single...

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Identifiers

PMID: 7768632
DOI: 10.1002/ijc.2910610505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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