p53 gene mutations in Barrett's epithelium and esophageal cancer.

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Article

p53 gene mutations in Barrett's epithelium and esophageal cancer.

Cancer research - 15 Aug 1991

Casson A G, Mukhopadhyay T, Cleary K R, Ro J Y, Levin B, Roth J A

Abstract excerpt

Genomic DNA was extracted from archival pathology specimens comprising 10 squamous and 14 adenocarcinomas, including 7 with Barrett's epithelium adjacent to tumor, and corresponding normal esophagus from the resection margin. The polymerase chain reaction was used to amplify selected exons of p53...

Topics

Adenocarcinoma
Barrett Esophagus
Base Sequence
Carcinoma, Squamous Cell
Cloning, Molecular
DNA, Neoplasm
Epithelium
Esophageal Neoplasms
Exons
Genes, Tumor Suppressor
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Polymerase Chain Reaction
Polymorphism, Genetic
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 1868473

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1868473-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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