Article
TP53 and gastric carcinoma: a review.
Human mutation - 1 Mar 2003
Fenoglio-Preiser C M, Wang J, Stemmermann G N, Noffsinger A
Abstract excerpt
In this article, we survey the major p53 (TP53) alterations identified in gastric carcinomas and their precursors. These include p53 expression, mutations, and loss of heterozygosity (LOH). Not only are the various abnormalities summarized, but in addition there is a survey of the literature with respect to the impact of these changes on patient prognosis and treatment response. The majority of published studies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
