[Mutation of p53 gene in human cancers of the esophagus and gastric cardia].

Article

[Mutation of p53 gene in human cancers of the esophagus and gastric cardia].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 May 1994

Li H C, Lu S X

Abstract excerpt

p53 gene in human esophageal cancer (EC) and cancer of gastric cardia was analyzed. Southern blotting hybridization revealed that five of 35 of EC sample were found to contain abnormal structure of p53 gene, including 2 deletions and 3 rearrangements; two of 27 adjacent non-tumor tissues also con...

Topics

Base Sequence
Carcinoma, Squamous Cell
Cardia
DNA, Neoplasm
Esophageal Neoplasms
Frameshift Mutation
Gene Deletion
Gene Rearrangement
Genes, p53
Humans
Molecular Sequence Data
Mutation
Point Mutation
Stomach Neoplasms

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