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Article

Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon.

Gastroenterology - 1 Dec 2003

Kato Takanobu, Date Tomoko, Miyamoto Michiko, Furusaka Akihiro, Tokushige Katsutoshi, Mizokami Masashi, Wakita Takaji

Abstract excerpt

BACKGROUND & AIMS: Although the hepatitis C virus (HCV) subgenomic replicon system has been widely used in the study of HCV, this system is available only for a few related genotypes. To develop a new replicon system, the genotype 2a clone JFH-1 was isolated from a patient with fulminant hepatitis. METHODS: A genotype 2a replicon was constructed by isolating the consensus sequence of JFH-1, transfecting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14724833
DOI: 10.1053/j.gastro.2003.09.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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