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Article

Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon.

The Journal of general virology - 1 Nov 2005

Targett-Adams Paul, McLauchlan John

Abstract excerpt

Dicistronic, subgenomic hepatitis C virus (HCV) replicons were constructed containing sequences from JFH1, a genotype 2a strain, that also incorporated the firefly luciferase gene under the control of the HCV internal ribosome entry site element. Luciferase activity in Huh-7 cell extracts containing in vitro-transcribed subgenomic JFH1 RNA was monitored over a 72 h period to examine early stages of HCV...

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Source

Identifiers

PMID: 16227230
DOI: 10.1099/vir.0.81334-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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