Article
Phenotypic characterization of three temperature-sensitive mutations in the vaccinia virus early gene transcription initiation factor.
The Journal of general virology - 1 Dec 1992
Christen L, Higman M A, Niles E G
Abstract excerpt
Vaccinia virus gene D6R encodes the small subunit of the virion early gene transcription initiation factor. Three temperature-sensitive mutations have been mapped to this gene. The biochemical phenotype exhibited by each mutation was examined. All mutants displayed altered viral protein synthesis...
Topics
- Gene Expression Regulation, Viral
- Genes, Viral
- Mutation
- Phenotype
- RNA, Messenger
- RNA, Viral
- Temperature
- Transcription Factors
- Transcription, Genetic
- Vaccinia virus
- Viral Proteins
- Viral Structural Proteins
- Virus Replication