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Article

Temperature-sensitive mutations in the vaccinia virus H4 gene encoding a component of the virion RNA polymerase.

Journal of virology - 1 Oct 1992

Kane E M, Shuman S

Abstract excerpt

Four previously isolated temperature-sensitive (ts) mutants of vaccinia virus WR (ts1, ts31, ts55, and ts58) comprising a single complementation group (R. C. Condit, A. Motyczka, and G. Spizz, Virology 128:429-443, 1983) have been mapped by marker rescue to the H4L open reading frame located within the genomic HindIII-H DNA fragment. The H4 gene is predicted to encode a 93.6-kDa polypeptide expressed at late...

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Identifiers

PMID: 1527841
DOI: 10.1128/JVI.66.10.5752-5762.1992
PMCID: PMC241450

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