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Article

Role of vaccinia virus A20R protein in DNA replication: construction and characterization of temperature-sensitive mutants.

Journal of virology - 1 Feb 2001

Ishii K, Moss B

Abstract excerpt

Previous analyses of randomly generated, temperature-sensitive vaccinia virus mutants led to the mapping of DNA synthesis negative complementation groups to the B1R, D4R, D5R, and E9L genes. Evidence from the yeast two-hybrid system that the D4R and D5R proteins can interact with the A20R protein suggested that A20R was also involved in DNA replication. We found that the A20R gene was transcribed early after...

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Identifiers

PMID: 11160663
DOI: 10.1128/JVI.75.4.1656-1663.2001
PMCID: PMC114074

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