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Article

Phenotypic characterization of mutants in vaccinia virus gene G2R, a putative transcription elongation factor.

Journal of virology - 1 Jan 1996

Black E P, Condit R C

Abstract excerpt

The phenotypic defects of two mutants of vaccinia virus, the lesions of which map to gene G2R, were characterized in vivo, and the results suggest a role for the G2R protein in viral transcription elongation. Both a temperature-sensitive mutant, Cts56, and an isatin-beta-thiosemicarbazone-dependent deletion mutant, G2A, in gene G2R have a characteristic and unique defect in late viral gene expression. The G2R...

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Identifiers

PMID: 8523560
DOI: 10.1128/JVI.70.1.47-54.1996
PMCID: PMC189786

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