A temperature-sensitive mutation of the vaccinia virus E11 gene encoding a 15-kDa virion component.

doi:10.1006/viro.1996.0057

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Article

A temperature-sensitive mutation of the vaccinia virus E11 gene encoding a 15-kDa virion component.

Virology - 1 Feb 1996

Wang S P, Shuman S

Abstract excerpt

The ts49 mutation of vaccinia virus WR was mapped by marker rescue to the E11 gene encoding a 15-kDa polypeptide. During synchronous infection of BSC40 cells with wild-type virus, immunoreactive E11 protein accumulated in parallel with the onset of late protein synthesis. Immunoblotting of extrac...

Topics

Chromosome Mapping
DNA, Viral
Gene Expression Regulation, Viral
Genes, Viral
Mutation
Temperature
Vaccinia virus
Viral Proteins
Virion

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