Article
A temperature-sensitive mutation of the vaccinia virus E11 gene encoding a 15-kDa virion component.
Virology - 1 Feb 1996
Wang S P, Shuman S
Abstract excerpt
The ts49 mutation of vaccinia virus WR was mapped by marker rescue to the E11 gene encoding a 15-kDa polypeptide. During synchronous infection of BSC40 cells with wild-type virus, immunoreactive E11 protein accumulated in parallel with the onset of late protein synthesis. Immunoblotting of extracts of wild-type virions showed that the E11 protein was encapsidated within the virus core. A normal temporal pattern...
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