Article
The vaccinia virus E8R gene product is required for formation of transcriptionally active virions.
Virology - 25 Oct 2007
Kato Sayuri E M, Condit Richard C, Moussatché Nissin
Abstract excerpt
Two vaccinia virus temperature-sensitive mutants were mapped to the E8R gene and subjected to phenotypic characterization. Dts23 contains a missense mutation in the coding region of E8R (L81F), and in Cts19 the initiating methionine codon is changed from ATG to ATA (M1I). The two ts mutants display normal patterns of gene expression and DNA replication during infection. The E8 protein is synthesized exclusively...
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