Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic characterization of a vaccinia virus temperature-sensitive complementation group affecting a virion component.

Virology - 1 Mar 1991

Fathi Z, Condit R C

Abstract excerpt

Genetic and biochemical evidence is presented which shows that the product of the vaccinia virus gene 18R is a virion protein. Western blot analysis of virion proteins using anti-18R serum detects a 78,000-Da protein, localized in the virus core. Of five ts mutants which map to gene 18R, two mutants, ts 10 and ts 44, possess thermolabile virions. Temperature shifts performed during single-step growth of ts 44...

Topics

Animals
Cell Line
Genes, Viral
Genetic Complementation Test
Phenotype
Temperature
Vaccinia virus
Virion

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1994577
DOI: 10.1016/0042-6822(91)90492-t

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1994577-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic characterization of a vaccinia virus temperature-sensitive complementation group affecting a virion component.PMID 1994577Read ↗

Temperature-sensitive mutants with lesions in the vaccinia virus F10 kinase undergo arrest at the earliest stage of virion morphogenesis.Semantic proximity Read ↗

The vaccinia virus E8R gene product is required for formation of transcriptionally active virions.Semantic proximity Read ↗

The vaccinia virus A18R protein plays a role in viral transcription during both the early and the late phases of infection.Semantic proximity Read ↗

Temperature-sensitive mutant in the vaccinia virus E6 protein produce virions that are transcriptionally inactive.Semantic proximity Read ↗

Phenotypic characterization of three temperature-sensitive mutations in the vaccinia virus early gene transcription initiation factor.Semantic proximity Read ↗

Temperature-sensitive mutations in the vaccinia virus H4 gene encoding a component of the virion RNA polymerase.Semantic proximity Read ↗

Vaccinia virus morphogenesis is blocked by temperature-sensitive mutations in the F10 gene, which encodes protein kinase 2.Semantic proximity Read ↗

A temperature-sensitive mutation of the vaccinia virus E11 gene encoding a 15-kDa virion component.Semantic proximity Read ↗

Characterization of ts 16, a temperature-sensitive mutant of vaccinia virus.Semantic proximity Read ↗

Genetic analysis of the vaccinia virus I6 telomere-binding protein uncovers a key role in genome encapsidation.Semantic proximity Read ↗

Vaccinia virus morphogenesis is blocked by a temperature-sensitive mutation in the I7 gene that encodes a virion component.Semantic proximity Read ↗

Unique temperature-sensitive defect in vaccinia virus morphogenesis maps to a single nucleotide substitution in the A30L gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.