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Article

Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysm.

Journal of vascular surgery - 1 Dec 2003

Jones Gregory T, Phillips Victoria L, Harris Eugenie L, Rossaak Jeremy I, van Rij André M

Abstract excerpt

PURPOSE: Matrix metalloproteinase-9 (MMP-9) is a potent endopeptidase with activity against both collagens and elastin. Expression of MMP-9 is elevated in vascular disease, and in particular within aneurysm tissues. This study tested the hypothesis that the functionally more active T allele of the MMP9 C-1562T polymorphism may be overrepresented in patients with abdominal aortic aneurysm (AAA) compared with...

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Share to Aged, 80 and over
Share to Aortic Aneurysm, Abdominal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Arteriosclerosis

Share to Gene Frequency

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Share to Peripheral Vascular Diseases

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 14681642
DOI: 10.1016/s0741-5214(03)01027-9

Genes

MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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