Article
Matrix metalloproteinase-9 genotype as a potential genetic marker for abdominal aortic aneurysm.
Circulation. Cardiovascular genetics - 1 Oct 2012
Duellman Tyler, Warren Christopher L, Peissig Peggy, Wynn Martha, Yang Jay
Abstract excerpt
BACKGROUND: Degradation of extracellular matrix support in the large abdominal arteries contribute to abnormal dilation of aorta, leading to abdominal aortic aneurysms, and matrix metalloproteinase-9 (MMP-9) is the predominant enzyme targeting elastin and collagen present in the walls of the abdominal aorta. Previous studies have suggested a potential association between MMP-9 genotype and abdominal aortic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.