C-reactive protein polymorphism rs3091244 is associated with abdominal aortic aneurysm.

doi:10.1016/j.jvs.2013.07.105

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Article

C-reactive protein polymorphism rs3091244 is associated with abdominal aortic aneurysm.

Journal of vascular surgery - 1 Nov 2014

Saratzis Athanasios, Bown Matthew, Wild Ben, Sayers Robert D, Nightingale Peter, Smith Jacqueline, Johnson Christopher, Kitas George

Abstract excerpt

BACKGROUND: Abdominal aortic aneurysm (AAA) formation involves an inflammatory process with a strong genetic background. C-reactive protein (CRP) regulates inflammation and is elevated in patients with AAA. The aim of this study was to investigate the association of the triallelic (C, A, and T alleles) rs3091244 functional CRP single nucleotide polymorphism (SNP) with AAA. METHODS: This was a case-control study...

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PMID: 24135623
DOI: 10.1016/j.jvs.2013.07.105

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