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Article

Multiple sites of vascular dilation or aneurysmal disease and matrix metalloproteinase genetic variants in patients with abdominal aortic aneurysm.

Journal of vascular surgery - 1 Jun 2018

Fiotti Nicola, Calvagna Cristiano, Sgorlon Giada, Altamura Nicola, Pitacco Paola, Zamolo Francesca, Di Girolamo Filippo Giorgio, Chiarandini Stefano, Biolo Gianni, Adovasio Roberto

Abstract excerpt

OBJECTIVE: The objective of this study was to assess whether functional genetic polymorphisms of matrix metalloproteinases (MMPs) 1, 3, 9, and 12 are associated with arterial enlargements or aneurysms of the thoracic aorta or popliteal arteries in patients with abdominal aortic aneurysm (AAA). METHODS: The associations between MMP1 (-1607 G in/del, rs1799750), MMP3 (-1171 A in/del rs35068180), MMP9 (13-26 CA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Aged, 80 and over
Share to Aortic Aneurysm, Abdominal
Share to Aortic Aneurysm, Thoracic
Share to Computed Tomography Angiography
Share to Dilatation, Pathologic
Share to DNA
Share to Matrix Metalloproteinases
Share to Risk Factors

Source

Identifiers

PMID: 29291905
DOI: 10.1016/j.jvs.2017.09.047

Genes

MMP12
MMP9
MMP1
MMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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