Article
Common FXIII and fibrinogen polymorphisms in abdominal aortic aneurysms.
PloS one - 1 Jan 2014
Macrae Fraser L, Evans Hannah Lee, Bridge Katherine I, Johnson Anne, Scott D Julian A, Ariëns Robert A S
Abstract excerpt
INTRODUCTION: Abdominal aortic aneurysms (AAA) are characterized by a progressive dilatation of the abdominal aorta, and are associated with a high risk of rupture once the dilatation exceeds 55 mm in diameter. A large proportion of AAA develops an intraluminal thrombus, which contributes to hypoxia, inflammation and tissue degradation. We have previously shown that patients with AAA produce clots with altered...
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