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Article

The alpha-2-antiplasmin Arg407Lys polymorphism is associated with abdominal aortic aneurysm.

Thrombosis research - 1 Sept 2014

Bridge Katherine I, Macrae Fraser, Bailey Marc A, Johnson Anne, Philippou Helen, Scott D Julian A, Ariens Robert A S

Abstract excerpt

INTRODUCTION: Abdominal Aortic Aneurysm (AAA) involves dilatation of the abdominal aorta, with a natural history of expansion and eventual rupture. We have previously shown that AAA patients form denser clots with smaller pores, which are more resistant to fibrinolysis. The aim of this study was to use functional polymorphisms of the fibrinolytic system to identify how changes to proteins involved in fibrinolysis...

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Identifiers

PMID: 25065555
DOI: 10.1016/j.thromres.2014.06.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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