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Article

The association of genetic variants of matrix metalloproteinases with abdominal aortic aneurysm: a systematic review and meta-analysis.

Heart (British Cardiac Society) - 1 Feb 2014

Morris Dylan R, Biros Erik, Cronin Oliver, Kuivaniemi Helena, Golledge Jonathan

Abstract excerpt

CONTEXT: Aberrant matrix turnover is believed to play a key role in the pathogenesis of abdominal aortic aneurysm (AAA). Matrix metalloproteinases (MMPs) and their inhibitors (tissue inhibitor of metalloproteinases; TIMPs) are important enzymes in the control of extracellular matrix remodelling. OBJECTIVE: The aim of this study was to investigate if single nucleotide polymorphisms (SNPs) within MMP and TIMP gene...

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Share to Aortic Aneurysm, Abdominal
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23813847
DOI: 10.1136/heartjnl-2013-304129

Genes

MMP3
MMP1
MMP10
MMP12
MMP13
MMP9
TIMP1
TIMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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