Article
Genetic complementation in female (BXSB x NZW)F2 mice.
Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2003
Kono Dwight H, Park Miyo S, Theofilopoulos Argyrios N
Abstract excerpt
F(1) hybrids among New Zealand Black (NZB), New Zealand White (NZW), and BXSB lupus-prone strains develop accelerated autoimmunity in both sexes regardless of the specific combination. To identify BXSB susceptibility loci in the absence of the Y chromosome accelerator of autoimmunity (Yaa) and to study the genetics of this complementation, genome-wide quantitative trait locus (QTL) mapping was performed on female...
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